Are you or a loved one living with Kidney Disease?
Learn about a no-cost, investigational treatment being studied for individuals living with APOL1-mediated kidney disease.

Have you checked your APOL1 status?
Certain chronic kidney conditions, like APOL1-mediated kidney disease (AMKD), are hereditary and can lead to increased protein levels in the urine due to kidney dysfunction. Understanding your or your loved one’s APOL1 status is crucial for assessing the risk of kidney disease.
APOL1-mediated kidney disease may be attributed to having a genetic variations (changes in DNA) in a gene called APOL1. While everyone has this gene, specific genetic differences can increase the risk of developing chronic kidney disease. Individuals of African descent are at a higher risk of having these gene variants and developing kidney disease or failure.
This clinical study, available at select centers across the U.S., offers genetic testing to determine if kidney disease is related to the APOL1 variations. If you meet the criteria and decide to participate, all study-related care and evaluations will be provided at no cost.
FILL OUT THE FORM BELOW IF YOU MEET THE FOLLOWING CRITERIA
- Are between 18 and 65 years of age
- Are of African descent (Black, African American, Afro-Caribbean, African, and/or Latino)
- Have been diagnosed with Chronic kidney disease
- Are not pregnant or breastfeeding
About the Study
APOL1-mediated kidney disease (AMKD) is a genetic condition that can impact multiple family members and can be passed down to younger generations. While current treatments manage the symptoms, no approved therapies address the underlying cause. This clinical trial aims to find a potential treatment that targets the underlying cause of AMKD, potentially leading to better therapies for those impacted by the disease. The research study involves taking an oral investigational medication once a day. The study will take up to 4 years to complete and includes genetic testing, trial-related medical examinations, kidney function assessment, ECGs, laboratory work, and other evaluations conducted by medical investigators. There will be no cost associated with participation in the trial. Additionally, you may receive reimbursement for transportation and the time required to participate.Why Participate?
If you or a loved one is struggling with Chronic Kidney Disease and want to know if the kidney condition is attributed to a genetic variation (changes in DNA) in a gene called APOL1, you may qualify for a research study now being offered at select centers throughout the U.S. If you qualify, you will receive:
No-cost Study Care
Study participants will receive study-related care from experienced doctors, nurses, and research staff.
Exams
The study will include genetic testing, kidney function assessment, ECGs, physical examinations, laboratory work, and other examination visits with a trained investigator.
Compensation
You might be eligible to receive reimbursement for time and travel.
Chat With a Research Coordinator
Fill out the form below, and you will be advised if you are eligible. If the initial screening criteria is met, you will be contacted by someone from a research location near you. If the minimum criteria is not met, please still submit the form. The study criteria may change in the future, and you or someone in your care might become eligible later.